This study is for people with gout. To qualify, you need to meet the following requirements:
- Ages 21 – 75, if female must not be of childbearing potential
- Have blood uric acid of 6mg/dL or higher (tested at screening visit)
- At least one gout flare in the last six months
This study involves weekly clinic visits for 6 months and up to 3 CT Scans at Wake Forest Hospital in Winston Salem. Visits are usually weekday mornings. Every 28 days, there is a 12 hour in-clinic infusion of the study medication. Meals are provided during infusion visits. All study medications and related treatments are free; you will be paid up to $2,500 for completing the study.
More than 8 million Americans suffer from gout. Gout occurs more often in men than in women. Men usually develop it between the ages of 30 and 50. Women are more prone to gout after menopause, and it is rare in children and young adults. Men who are overweight or suffering from high blood pressure are particularly prone to gout, especially if they are taking thiazide diuretics (water pills).
Gout is actually a form of arthritis. It is the body’s reaction to irritating crystal deposits in the joints. The pain can be intense, but treatment usually works very well. Mild cases may be controlled by diet alone. Recurring attacks of gout may require long-term medication to prevent damage to bone and cartilage and deterioration of the kidneys.
Chronic gout sufferers may feel tiny, hard lumps accumulating over time in the soft flesh of areas such as the hands, elbows, feet, or earlobes. These deposits, called tophi, are concentrations of uric acid crystals and can cause pain and stiffness over time. If similar deposits form in the kidneys, they can lead to painful and potentially dangerous kidney stones.
You may benefit from potential new therapies in a clinical trial before they are generally available and you will most definitely be helping improve healthcare options for everyone.