This is a clinical trial for patients with diabetes who suffer from delayed digestion sometimes called gastroparesis. To qualify, you need to meet the following requirements:
- Type 1 or type 2 diabetes diagnosed at least 5 years ago
- HbA1c of 11 or below (tested at screening)
- BMI between 18 and 36
- At least 3 months of symptoms including: vomiting, nausea, early full feeling when eating, extended full feeling after eating, bloating or pain
- Recent vomiting episodes
This is a 52-week study requiring up to 9 visits in our Greensboro clinic, with one or two visits requiring up to 5 hours for digestion testing. Visits are usually weekday mornings. All study medications and related treatments are free; you will be paid up to $500 for completing the study.
Over time, diabetes can affect many parts of your body. One of those is the vagus nerve, which controls how quickly your stomach empties. When it’s damaged, your digestion slows down and food stays in your body longer than it should. This is a condition called gastroparesis. It can make you feel queasy and vomit. It’s also bad for your blood sugar levels. Although it’s more common in people with type 1 diabetes, people with type 2 can also get it. Most people with gastroparesis have had diabetes for at least 10 years and also have other complications related to the disease.
Gastroparesis symptoms include:
- Heartburn or reflux (backup of stomach contents into the esophagus)
- Vomiting (in severe cases, this may happen daily)
- Trouble controlling blood sugar
- Feeling full quickly when eating
- Abdominal bloating
- Poor appetite and weight loss
Food that stays in your stomach too long can spoil and lead to the growth of bacteria. Undigested food can harden and form a lump called a bezoar. It can block your stomach and keep what you eat from moving into the small intestine. Gastroparesis can make it hard to control diabetes. When food finally does leave your stomach, and enters the small intestine, your blood sugar goes up, too. Throwing up can also leave you dehydrated.
You can benefit from potential new therapies in a clinical trial before they are generally available and you will most definitely be helping improve healthcare options for everyone.